Oscar U. Scremin, MD, PhD

Professor Emeritus, Department of Physiology, David Geffen School of Medicine at UCLA

Dr. Scremin studies regulation of blood flow in cerebral and peripheral tissues; its modification by acetylcholine, by potassium channels, and by neuropeptides; cerebral metabolic activation in the setting of brain injury utilizing autoradiographic methodologies. Regional cerebral blood flow and glucose utilization, the concentrations of acetylcholine (ACh) and its precursor choline, as well as cholineacetyltransferase activity, and the turnover rate of ACh are assessed in relation to cognitive function. Dr. Scremin is presently analyzing the effects of stimulation of the cholinergic system on the behavioral and motor deficits associated with brain trauma.