- About CURE
Dennis Jensen, MD
Professor, Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine at UCLA
Dr. Jensen is Associate Director of the CURE: DDRCC, Director of the Human Studies Core and of the UCLA Training Grant in Gastroenterology. His research interests are GI randomized controlled trials, GI hemorrhage, Barrett’s epithelium, portal hypertension and varices, GI endoscopy, and technology assessment of GI therapeutic endoscopy techniques. The studies of Barrett’s epithelium include a randomized study of endoscopic ablation, a histopathologic study of progression to dysplasia, secondary prevention of Barrett’s recurrence after ablation, and a study of potential biomarkers in progression to cancer. The K24 grant and others also support a randomized prospective study of primary prophylaxis to present first variceal hemorrhage with medical therapy with hepatic wedge pressure gradient monitoring compared to endoscopic rubber band ligation. Dr. Jensen is also prospectively studying outcomes of patients with severe hematochezia (with a new instrument for stratifying risk), severe obscure GI bleeding (with capsule endoscopy and intraoperative enteroscopy), and gastric variceal hemorrhage (natural history and secondary prevention of recurrence). He also is evaluating the accuracy of Rome II criteria without or with capsule endoscopy for diagnosis of IBS. He is also studying new techniques of endoscopic control of GI hemostasis in a canine model of esophagogastric varices. The NIH training grant supports M.D.’s and/or PhD’s whose research is basic, translational, clinical, or health services. Most trainees utilize core services for their research.