- About CURE
Stephen Young, PhD
Assistant Researcher, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine at UCLA
Dr. Young is a physiologist and biophysicist who is an expert in cellular imaging. He has studied propagation of Ca2+ waves between colonic smooth muscle cells in culture and intercellular communication between dorsal root ganglion cells in colonic smooth muscle cells. He currently studies the mechanism by which activation of the extracellular Ca2+ sensing receptor induces intracellular Ca2+ oscillations in response to stimulation by extracellular calcium or amino acids. In view of the intense interest of most CURE: DDRCC members in the expression, trafficking and signaling via GPCRs, Dr. Young collaborating with J. Enrique Rozengurt, is attempting to exploit the physical properties of Quantum dots to label GPCRs in a variety of cell types, including colon and pancreatic cancers cells. He plays a major role in the Morphology/Imaging Core and interacts closely with many the members of the Hormones and Signal Transduction program.