S. Vincent Wu, PhD

Dr. Wu has studied structure-function relationships in CCK receptors and has used mutational analysis to demonstrate a site on the CCK-A receptor responsible for coupling to Gs and stimulation of cyclic AMP production through this receptor.  He has also identified transcripts encoding bitter taste receptors in rodent and human gastrointestinal tissues as well as in enteroendocrine cell lines and has also characterized their genomic localization, tissue expression and cellular functions.