- About CURE
Jingzhen Yuan, PhD
Assistant Researcher, Department of Medicine, David Geffen School of Medicine at UCLA
Dr. J. Yuan studies the regulation of protein kinase D (PKD) isoenzymes by GI peptides and pro-inflammatory mediators. Her research is focused on the molecular and signaling mechanisms by which PKD family members PKD-1, PKD-2, and PKD-3 are activated by GI peptides. She is elucidating the molecular mechanisms of action of cholecystokinin (CCK) in the regulation of PKD and PKC in pancreatic acinar cells and is identifying the role of PKD/PKC in specific inflammatory pro-inflammatory pathways in acute and chronic pancreatitis. Dr. Yuan has been a recipient of the CURE: DDRCC Pilot and Feasibility award.