CURE initially established its reputation for work in clinical peptic ulcer disease, physiological regulation of acid secretion, and parietal cell mechanisms for secreting acid. Demonstration that Helicobacter pylori is an essential factor in pathogenesis of ordinary peptic ulcer disease brought new aspects of mucosal cell biology into the forefront of research at CURE. The interest and activities of Center members have evolved along with science in this area and now include several facets of gastrointestinal regulatory physiology and cell biology. CURE's new name reflects more appropriately the broad interests of its members, including gastroduodenal mucosal physiology and disease; intestinal transport, intestinal inflammation, nutrition, and pancreatic secretion; neurophysiology and neuroenteric diseases; and hormones, receptors, and signal transduction.

CURE Director: Enrique Rozengurt, D.V.M., Ph.D.

Associate Directors:
Dennis Jensen, M.D.
Yvette Taché, Ph.D.
Catia Sternini, M.D.
Ernest Wright, D.Sc.

Administrative Core

Director:	Enrique Rozengurt, D.V.M., Ph.D.
Co-Director:	Emeran Mayer, M.D.
Administrator:	Jacqueline Ismen, B.A.
Programmer Analyst:	Alexander Khamudis, M.S.
Phone:	310-312-9284
Fax:	310-268-4963
Email:	cureadmn (at) mednet.ucla.edu

Animal Models Core

Director: Yvette Taché, Ph.D.
Co-Director: Jonathan Kaunitz, M.D.
Associate Director: Million Mulugeta, DVM, Ph.D.

Human Studies Core

Director: Dennis Jensen, M.D.
Associate Directors: Lin Chang, M.D., Brennan Spiegel, M.D., MSHS
Associate Director: Thomas O.G. Kovacs, M.D.

Morphology/Imaging Core

Director: Catia Sternini, M.D.
Associate Directors: Nicholas Brecha, Ph.D., Nora Rozengurt DVM, Ph.D.

Peptidomics/RIA/Proteomics Core

Director: Joseph R. Reeve, Jr., Ph.D.
Co-Director: David Keire, Ph.D., Gordon Ohning M.D., Ph.D., Kym Faull, Ph.D.

Molecular Biology and Vector Core

Director: Noriyuki Kasahara, M.D., Ph.D.
Co-Director: Renata Stripecke, Ph.D.